Disclaimer: This content is for educational purposes only. It is not medical advice. Consult a qualified healthcare provider before starting any supplement regimen. Some compounds listed may require a prescription in your jurisdiction.
The Founder Stack
A tiered guide to health optimization compounds — from foundational supplements everyone should consider, to advanced protocols for experienced biohackers. Click any compound for detailed dosing, safety, and evidence data.
Everyone Should Be Doing This
Over-the-counter, decades of research, no controversy. You're leaving performance on the table without these.
Electrolytes (Na/K/Mg)
OralMost underrated performance hack — chronic dehydration tanks cognition and energy.
L-Theanine
OralSmooths out caffeine jitters and promotes calm focus without sedation.
Magnesium Threonate
OralThe only magnesium form proven to cross the blood-brain barrier — supports sleep and cognition.
Omega-3 (EPA/DHA)
OralFoundational for brain cell membrane health and reducing neuroinflammation.
Creatine
OralNot just for the gym — 5g/day improves working memory and mental endurance under stress.
Vitamin D3 + K2
OralMost people are deficient — supports mood, immune function, and hormone production.
Ashwagandha (KSM-66)
OralLowers cortisol 25-30% in clinical trials — directly counters chronic stress.
CoQ10 / Ubiquinol
OralMitochondrial energy production declines after 30 — this supports restoring it.
Rhodiola Rosea
OralAdaptogen that improves fatigue resistance under stress — strong clinical evidence.
Taurine
OralLongevity compound that depletes with age — supports cardiac function and neuroprotection.
Biohacker Curious
Oral bioregulators, nasal peptides, advanced nootropics. Solid research but you need to know what you're doing.
Pinealon
CapsuleKhavinson bioregulatory peptide that supports pineal function and circadian rhythm regulation.
Epitalon
CapsuleFlagship Khavinson peptide with 20+ years of published research on telomerase activation and longevity.
Selank
NasalAnxiolytic cognitive enhancer without sedation — modulates GABA and serotonin systems.
Semax
NasalBoosts BDNF to enhance focus, memory, and neuroprotection.
Bromantane
OralUpregulates dopamine synthesis (not release) — sustainable motivation without tolerance.
Methylene Blue
OralEnhances mitochondrial electron transport chain — supports brain energy at low doses.
Modafinil / Armodafinil
RxWakefulness agents that support focus and executive function.
Tadalafil (Low-Dose)
RxPDE5 inhibitor that supports blood flow, cardiovascular health, and exercise performance at daily low dose.
Full Optimization
Injectables, advanced nootropics, research compounds. Frontier stuff — real commitment required.
Tirzepatide / Retatrutide
InjectableGLP-1 metabolic optimization — appetite regulation and metabolic health without increased resting heart rate.
SS-31 (Elamipretide)
InjectableThe most direct mitochondrial repair peptide — targets cardiolipin in the inner mitochondrial membrane.
MOTS-c
InjectableMitochondrial-derived peptide that regulates metabolic homeostasis and cellular energy.
GH / IGF-1 Optimization
InjectableGrowth hormone optimization for recovery, sleep quality, body composition, and longevity.
KLOW Blend (BPC-157 / TB-500 / GHK-Cu / KPV)
InjectableRegenerative peptide stack — tissue healing, systemic repair, gene expression reset, and inflammation suppression.